Aleksandar Mitrovic’s 38th goal of the season moved leaders Fulham 21 points clear of the Championship’s Play-Off zone as they claimed a 1-0 win at Middlesbrough.
The Cottagers, on course for an immediate return to the Premier League, secured yet another victory with Marco Silva’s men now 11 points clear of second-placed Bournemouth.
The Serbian’s header with 17 minutes remaining proved enough for all three points with Fulham now potentially being promoted as early as this weekend.
In Tuesday night’s games, Millwall’s seven-game unbeaten home run came to an abrupt end with a 1-0 defeat to Swansea City.
Joel Piroe’s strike in the opening minute of the second-half proved decisive to leave the Lions in 10th, four points off the Championship Play-Offs.
Just above them are QPR who were also dealt a blow to their promotion hopes, losing 1-0 to Sheffield United at Bramall Lane.
An early goal from Oliver Norwood was enough to pile further pressure on Hoops boss Mark Warburton following a run of just two wins in their last 12 league games.
And in League One, Zach Robinson’s dramatic late leveller rescued AFC Wimbledon a point as they drew 1-1 with 10-man Charlton Athletic at Plough Lane.
The visitors went ahead through Jayden Stockley midway through the second half after a dangerous tackle from Ryan Inniss had reduced them to 10 men.
But Robinson’s 87th-minute equaliser gave the struggling Dons some hope of survival to leave them four points adrift of 20th-place Morecambe in the table.