Arsenal got their season up and running by coasting to a 6-0 victory at West Bromwich Albion with Pierre-Emerick Aubameyang hitting a hat-trick.
The forward will not have scored many easier goals than the first-half brace he grabbed before adding a fine third for the match ball as Nicolas Pepe, Bukayo Saka and Alexandre Lacazette also found the back of the net.
In Tuesday night’s games, last season’s Carabao Cup giant killers Brentford almost got a taste of their own medicine before coming from behind to beat Forest Green Rovers 3-1.
The Bees, who knocked out four top-flight sides on their way to the semi-finals last year, fell behind to an early goal from Rovers’ Jack Aitchison.
However, goals in the final 30 minutes from Yoane Wissa, Bryan Mbeumo and Marcus Forss won it for Thomas Frank’s Premier League side.
Millwall also came from behind as two goals in three first-half minutes from Murray Wallace helped the Lions beat Cambridge United 3-1 at The Den.
The League One side led for just six minutes through George Williams’ header before Wallace’s brace with Matt Smith rounding off the scoring early in the second-half.
Meanwhile, Rob Dickie scored a brilliant goal against his former club as QPR eased to a 2-0 victory over Oxford United at the Kiyan Prince Foundation Stadium.
Dickie’s 26th-minute opener, the centre-back’s fourth goal of the season, and Leon Chambers-Parillon’s own goal five minutes before half-time saw the Hoops claim a routine win.
Fulham also coasted into the next round with a 2-0 away win at Birmingham City, courtesy of goals fromJay Stansfield and Antonee Robinson.
Elsewhere, Anthony Hartigan’s added-time strike secured AFC Wimbledon a 1-0 win at Northampton Town while a late strike from Ashley Fletcher sent Watford through at Crystal Palace’s expense.
THIRD ROUND DRAW (LONDON TIES)
Arsenal vs AFC Wimbledon
Brentford vs Oldham Athletic
Chelsea vs Aston Villa
Fulham vs Leeds United
Manchester United vs West Ham
Millwall vs Leicester
QPR vs Everton
Wolves vs Tottenham
Ties to be played week beginning September 20.